THOMAS KING

 Office: Copernicus 204
Lab: Copernicus 429 (Animal Suite) 860-832-2654
kingt@ccsu.edu

Courses Taught:

Research Interests:

My research interests concern the genetic analysis of development in mammals, using mice and rats as model mammalian systems. With the long-term goal of gaining access to the molecular biology underlying interesting mutant phenotypes, my laboratory has made progress pursuing four different projects: 1) We are investigating the molecular genetic basis of a pleiotropic developmental mutation in the mouse, designated mshi. 2) We are initiating a phenotypic and genetic characterization of a hairless mutant (called “shorn”) that arose spontaneously in CCSU’s laboratory rat colony. 3) Another project has suggested Fgfr2 as a possible gene candidate for the Charles River “hairless” mutation, which we have shown is an allele of rat fuzzy and a likely orthologue of mouse frizzy. 4) We are now intensively pursuing a series of experiments aimed at identifying minor histocompatibility loci on the mouse X chromosome that might differ between standard inbred mouse strains

Recent Publications:

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Revised December 08, 2006